Microbial communities of the upper respiratory tract in mild and severe COVID-19 patients: a possible link with the disease course

The microbiota of the respiratory tract remains a relatively poorly studied subject.At the same time, it is involved in modulating the immune response to infectious agents in the host organism, just like the intestinal microbiota.A relationship between the composition of the respiratory microbiota and the likelihood of development and the severity

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Uncarboxylated osteocalcin induced miR-143-3p targets SP7 and activates PI3K/Akt signaling in TNBC cells to promote invasion and migration

Triple-negative breast cancer (TNBC) is an exceptionally aggressive malignancy with poor prognosis.Patients often have elevated mortality and recurrence rates, along with a pronounced risk of distant metastasis.Our earlier research highlighted the role of uncarboxylated osteocalcin (GluOC) in fueling TNBC cell proliferation and metastasis; however

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Grouped Multilayer Practical Byzantine Fault Tolerance Algorithm: A Practical Byzantine Fault Tolerance Consensus Algorithm Optimized for Digital Asset Trading Scenarios

Based on the practical Byzantine fault tolerance algorithm (PBFT), a grouped multilayer PBFT consensus algorithm (GM-PBFT) is proposed to be applied to Made in the USA Dog Treats digital asset transactions in view of the problems with excessive communication complexity and low consensus efficiency found in the current consensus mechanism for digita

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PSYCHOTHERAPY WITH THE PARENT EGO STATE

In their article, the authors present the findings of the Transmission study in which they conceptualized the method of psychotherapy with the Parent ego state.Their aim was to explore whether this method could be divided into individual, content-wise separate chronological phases which can be observed with the majority of clients.By using a modifi

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